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This medicine contains live, attenuated mycobacteria, and is used
in the treatment of superficial bladder
cancer. It helps to reduce the frequency of recurrent tumors and
may also reduce the risk of disease progression.
Who can benefit from this treatment?
The most common type of bladder cancer is called transitional
cell carcinoma. Most patients will present with superficial
tumors, which involve only the innermost lining of the bladder wall,
as opposed to muscle-invasive tumors.
High-grade tumors and carcinoma in-situ are two main
indications for BCG treatment after undergoing initial surgery (transurethral
resection) to remove the tumors. Other indications include cases
involving multiple tumors (>2), large tumors, and in those patients
who have history of frequent recurrences.
When and How is BCG given?
BCG treatment usually starts no earlier than 2 weeks after the initial
transurethral resection. The medicine is instilled into the bladder
by gravity through a catheter, a procedure done in the doctor's
office. The initial course is usually once a week for 6 weeks. Patients
are often reevaluated after this initial course to determine response,
which may involve repeat biopsy of the bladder, especially the area(s)
of the original tumor(s). Additional courses or doses may be recommended
depending on the particular circumstances of your case.
For each weekly dose, patients are asked to retain the medicine
in the bladder for about 2 hours and then voided. In order to achieve
maximum time of bladder surface contact with the medicine, the bladder
is emptied before instillation, and patients are asked to avoid
drinking fluids during this 2-hour period to avoid the need to urinate.
What special handling is required for proper
disposal of this medicine?
Since this medicine contains live bacteria, it must be properly
disinfected. Patients should void while seated in order to avoid
splashing of urine. For the 6 hours after treatment, urine voided
should be disinfected for 15 minutes with an equal volume of household
bleach before flushing the toilet. Patient should also increase
fluid intake to "flush" the bladder during this time.
What can I expect to feel during treatment?
You may experience burning with first few voids after treatment.
The more common symptoms are low-grade fever, headache, malaise,
and mild flu-like symptoms. Relief can be obtained with over the
counter medications such as Tylenol. If you are having high, persistent
fever, chills, visible blood in the urine, or other symptoms such
as joint pain, cough, or skin rash, please contact your doctor immediately.
Special Precautions
Females of childbearing are: Tell your doctor if you are pregnant
or breast-feeding.
Tell your doctors if you are an organ-transplant recipient and taking
immunosuppressive drugs or taking similar drugs (chemotherapy drugs,
steroids) for other illnesses.
Betamethasone - Clotrimazole
This is medicated ointment, lotion, or cream used externally to
treat fungus infection of the skin. It also contains a steroid (Betamethasone)
to help reduce inflammation of the involved area.
How is it used in Urology?
It is used in patients with fungal infection involving the areas
of the genitalia. This is a particularly common problem in persons
with diabetes, especially in those who have poor control of their
condition. Patients with urinary incontinence may also experience
similar problem.
Proper Use
Use this medicine only for the condition for which it was prescribed.
Using your fingers apply a thin layer on the affected area. DO NOT
GET THIS MEDICINE IN YOUR EYES OR IN OPEN WOUNDS. Do not cover the
area with a bandage unless instructed by your doctor.
This medicine is not recommended for treating diaper rash in babies
or small children.
Possible Side Effects
Report to your doctor if you have worsening redness, irritation,
swelling, or pain.
Possible Drug Interactions
Do not use with any other medicated cream, lotion, or ointment.
Do not use with strong soap, medicated cosmetics, or products containing
alcohol.
Bethanechol (Urecholine® 25mg)
This medicine is used to improve urination and bladder emptying
in patients whose bladder muscle has weakened.
Proper Use
This medicine works best when taken on an empty stomach, 1 hour
before or 2 hours after meals, unless your doctor tells you otherwise.
Take this medicine as directed by your doctor. Typical starting
dose is 25 mg three times a day. Do not take double dose even if
you had missed a dose. To avoid interrupting your sleep at night,
take the last dose of the day before 6 PM.
What are the more common side effects?
Side-effects occur in varying degree and include dizziness, lightheadedness,
diarrhea, headache, nausea, and vomiting. By taking the medication
as directed above, nausea and vomiting can be avoided. Notify your
doctor immediately if you are experiencing trouble breathing, chest
tightness, or severe stomach cramp or ache.
Possible Drug Interactions
Talk to your doctor if your are taking any of these medicines:
Quinidine (Quinora, Quinaglute, Quinalan, Cardioquin)
Procainamide (Pronestyl)
Nitrates (Isordil) and nitroglycerin (Nirostat, Nitrolingual,
Nitrong, Nitro-Dur, Nitrol)
Ganglionic blocking agents
Bicalutamide
In urology, this is an anti-androgen medicine used in the treatment
of advanced prostate cancer.
How and When is it used?
It is more commonly used along with another class of medication
called LHRH agonists (Lupron, Zoladex). In most cases it is used
to block the testosterone flare which is seen during the first few
weeks of starting a LHRH agonist. In certain patients, long -term
use is indicated. You may take this pill with or without food.
What are the side effects?
The most common side effect of hormonal treatment for prostate cancer
is hot flashes (redness and warm feeling of your face and neck areas).
Some men will also notice gradual breast enlargement (gynecomastia)
when taking anti-androgens. Others may experience nausea, vomiting,
abdominal pain, loss of appetite, constipation and diarrhea.
Your liver function is regularly monitored to detect any potential
effects on its function since this medicine is metabolized through
the liver. Notify your doctor immediately if you see dark color
urine, or yellowing of your skin or eyes.
Possible Drug Interactions
Medications metabolized by the liver may be affected by concurrent
use of anti-androgens. This would include blood thinners such as
warfarin (Coumadin) and closer monitoring of its effect is needed.
Ciprofloxacin (Cipro®)
This is a fluoroquinolone antibiotic commonly used in bacterial
urinary tract infections. It is also used for other conditions.
Proper Use
For outpatient therapy, this antibiotic is taken by mouth twice
a day. It is best to take this medicine 2 hours after a meal unless
otherwise directed by your doctor. Avoid taking it along with other
medications especially iron, antacids containing aluminum or magnesium,
multivitamins, sucrafate (Carafate), and didanosine (Videx).
Please Note - Side Effects
-Tell your doctor if you have ever had seizures. If you have a seizure
while taking this medicine, stop taking it and contact your doctor.
-If you are a diabetic using insulin or taking diabetes medicine
by mouth and you have symptoms of low blood sugar, immediately contact
your doctor. Symptoms include confusion, shaking, weakness, strong
hunger, cold sweats, headache, nausea, vision problems, and feeling
faint.
-Allergic reaction to this medicine presents as hives, itching,
tightness in your chest, or trouble breathing. Contact your doctor
immediately or get emergency medical care.
-This medicine may cause drowsiness. Do not drive or operate machinery
unless you are fully alert.
-This medicine may increase the effects of caffeine in coffee, black
tea, and colas. You may feel shaky and have trouble sleeping.
-This medicine may make your skin more sensitive to the sun, even
when you use sunscreen. While you taking this medicine, avoid long
exposure to the sun. Do not use a sunlamp.
-Women of childbearing age: this medicine is not usually given during
pregnancy. Tell your doctor if you are pregnant or plan to become
pregnant during treatment. Do not breast-feed while taking this
medicine.
Possible Drug Interactions
Talk to your doctor if you are taking any of the following medicines:
- amiodarone (Cordarone)             - antacids
(Maalox, Mylanta)
- cimetidine (Tagamet)              
    - cyclosporine (Sandimmune, Neoral)
- didanosine (Videx)                
     - digoxin (Lanoxin)
- disopyramide (Norpace)             - erythromycin
(Erythrocin, EES, EryPed)
- glyburide (DiaBeta, Glynase)       - medicines with
caffeine
- multivitamins with iron or zinc       - nitrofurantoin
(Macrodantin)
- Pepto-Bismol                  
           - phenytoin (Dilantin)
- probenecid (Benemid)              
  - procainamide (Pronestyl, Procan)
- quinidine (Quinora, Quinidex, Quinaglute, Cardioquin)
- sotalol (Betapace)                
      - sucrafate (Carafate)
- theophylline (Theo-Dur, Slo-Bid) - thioridazine (Mellaril)
-tricyclic antidepressants such as amitriptyline (Elavil), desipramine
(Norpramin), nortriptyline (Aventyl, Pamelor), imipramine (Tofranil),
and doxepin (Sinequan)
- warfarin (Coumadin) or other blood thinners.
Cranberry
Cranberry plants grow as small, trailing evergreen shrubs. Their
flowers range from pink to purple, and bloom from May to August,
depending on the type. The berries are harvested in the fall. Common
names are small cranberry, southern mountain cranberry, lowbush
cranberry, and highbush cranberry.
How is cranberry used in urology?
Cranberries and their juice have been used for treating and preventing
urinary tract infections. Its juice has a promising use as a urinary
deodorant. The bad odor of fermenting urine from people who have
lost bladder control is a common problem in hospitals and long-term
care facilities. Drinking cranberry juice helps stop the odor by
slowing down the bacteria that ferment the urine.
How are cranberries taken?
You can eat the fruit or drink the juice. There has been some recent
scientific proof of benefit for prevention of urinary tract infections.
Cranberry is also available in capsules.
What are the side effects?
Extremely large amounts of cranberry juice can produce stomach pain
and diarrhea. Rarely, people are allergic to cranberries.
Cranberry is considered a natural remedy. Unfortunately, "natural"
does not always mean safe. Natural remedies and prescription medicines
may interact. Lack of standardization may result in products with
different strengths and effects. Lack of quality control may allow
contamination of products. If you are pregnant or breast-feeding,
you should ask your obstetrician before taking any natural remedy.
Long-term use and increasing dosages are not recommended. Infants,
young children and the elderly should also not use natural remedies
without seeking professional advice.
Doxazosin (Cardura®)
This medicine was originally used to treat and control high blood
pressure. Many men who were taking it also reported improvement
of the urinary voiding symptoms. As such, it is also currently used
for men with bothersome voiding symptoms secondary to prostate enlargement
(BPH).
Proper Use
This medicine is taken by mouth, usually in the evening hours. Do
not take double doses at one time. If you miss a dose, take it as
soon as you remember unless it is almost time for the next scheduled
dose. Dose can be adjusted to achieve maximum potential benefit,
however, the risk of side effects may also increase.
Please Note
You may feel dizzy, lightheaded or faint when you get up quickly
after sitting or lying down. Getting up slowly may help. If you
are consistently feeling dizzy, contact your doctor.
Alcohol, exercise, and hot weather may also make you feel dizzy,
lightheaded, or drowsy. Avoiding these factors is important, especially
after you take the first few doses, after your dosage is increased,
and when you start taking the medicine again after some time without
it.
Rarely, this medicine may cause a painful erection of the penis
that will not go down. If this occurs, contact your doctor immediately.
Other problems include nausea, weakness, fatigue, drowsiness, stomach
pain, nervousness, headache, vomiting, and vision problems. Contact
your doctor immediately for irregular or fast heartbeat, fainting,
chest pain, trouble breathing, swelling in your hands or feet, loss
of feeling in your hands or feet, and severe or constant headache.
Estradiol Cream (Estrace®)
Estrogens have important benefits but also some risks. This medicated
cream is used to treat thinning of the vaginal lining caused by
the lack of estrogen. Since it is applied directly to the affected
area, less medication is needed and its absorption into the blood
stream is minimized thereby reducing the risk of systemic side effects.
Proper Use
This is a vaginal cream, which can be applied with a fingertip.
Do not use more of it or use it longer than prescribed. Wearing
sanitary pads while you are using this cream will help protect your
clothing.
Please Note
Exposure to the sun and sunlamps while you are using this medicine
may cause dark spots to appear on your skin. This problem is usually
self-limiting.
Contact lenses may feel uncomfortable while you are using this medicine.
Do not use this medicine if you are pregnant or plans to become
pregnant while using this cream.
Smoking while using this medicine increases the risk of side effects.
Common side effects include nausea, swollen/tender breasts, cramps,
and bloating. Notify your doctor if you are experiencing swollen
ankles or feet, changes in menstrual periods, breast discharge,
or vaginal irritation.
Possible Drug Interactions
Talk to your doctor if you are taking any of the following medicines:
- blood thinners (warfarin)       - carbamazepine (Tegretol)
- cortinsone-like drugs such as cortisone (Cortone), dexamethasone
(Decadron, Hexadrol) hydrocortisone (Hydrocortone, Cortef), prednisone
(Meticorten, Deltasone)
- dantrolene (Dantrium)           - Phenobarbital
- phenytoin (Dilantin)              
- primidone (Mysoline)
- rifampin (Rifadin, Rimactane)
- tricyclic antidepressants such as amitriptyline (Elavil), nortriptyline
(Aventyl, Pamelor), imipramine (Tofranil), and doxepin (Sinequan).
Finasteride (Proscar®)
This medicine is taken by mouth to (1) shrink an enlarged prostate
gland that may be causing your symptoms and voiding difficulties,
(2) reduce the risk of inability to pass urine (urinary retention),
and (3) reduce the chance you will need prostate surgery. This is
only effective in a limited group of patients. Your urologist can
determine its potential benefit to you.
Proper Use
This medicine is usually taken once a day (5 mg), with or without
food. The potential shrinking effect of the prostate gland generally
takes several months.
Please Note
This medicine is usually given to men only. Women and children should
not take this medicine. Women who are pregnant or may become pregnant
should not take this medicine.
This medicine can affect a blood test called PSA, which is used
to screen men for prostate cancer. Inform your doctor of your taking
this medicine for proper interpretation of your PSA result.
This medicine may cause impotence (trouble having and keeping an
erection), decrease your sex drive, or reduce the amount of semen
released during sexual intercourse. These effects are mild and temporary
when they occur.
Do not expose your partner to your semen if she is pregnant or can
become pregnant. Use a condom under these circumstances.
Possible Drug Interactions
Tell your doctor if you are taking theophylline, a medication used
to treat asthma and other breathing problems.
Possible Food Interactions
The effects of this medicine may be increased if you take it with
grapefruit juice. Tell your doctor about all medicines you are taking,
including over the counter products, vitamins, and natural remedies.
Goserelin Acetate Implant (Zoladex®)
The medicine is an implant placed just under the skin to treat advanced
prostate cancer. It produces an effect of castration as it shuts
down testosterone production from the testicles. In women, it is
sometimes used for breast cancer and endometriosis.
How is it given?
This medicine comes either as a one-month formula or multi-month
formula (3 or 4 months). The implants are designed to allow slow
release of the drug into your body. It is commonly implanted under
the skin over the abdominal area, an office procedure performed
with minimal local anesthesia.
Please Note
Diabetics: This medicine may affect your blood sugar level and change
the amount of insulin or other diabetes medicines you may need.
Closer monitoring may be required and your dosing may need to be
adjusted.
When you first start this particular treatment, there is usually
a surge in your blood testosterone level. As such, some of your
voiding symptoms or pain may worsen. To blunt this effect, another
medicine (an anti-androgen) is often given concurrently for the
first two weeks.
Other side-effects may occur after long term use of this medicine
and may include elevation of total blood cholesterol and triglycerides,
osteoporosis, anemia (low red cell blood count), hot flashes, sexual
problems, decreased erections, loss of appetite, and fatigue.
No significant drug interactions have been reported to date. However,
be sure to update your doctors about all medicines you are taking,
including over the counter medications, vitamins, and natural supplements.
Hyoscyamine (Levsin®, Cystospaz®)
This medicine is in a class of drugs called belladonna alkaloids,
and is used to relieve symptoms of bladder spasm, by relaxing the
smooth muscles of the bladder. Since other systems or organs (stomach
and intestines) also contain similar smooth muscles, it is also
commonly used for certain gastrointestinal conditions.
Proper Use
This medicine works best when taken 30 minutes to 1 hour before
meals. If you are taking antacids, take them 2 hours before or after
you take this medicine. There is also a faster onset formulation,
which is taken sublingually (under the tongue) and avoids stomach
absorption problems.
Do not take more than directed. Do not take double doses. If you
miss a dose, take it as soon as you remember unless it is almost
time for the next scheduled dose. In that case, skip the missed
dose and take the next one as directed.
Please Note
Common side effects include dry mouth, constipation, and decreased
sweating. It may also cause blurred vision, dizziness, or drowsiness.
Due to these potential side effects, do not drive or operate machinery
unless you are full alert and can see clearly. Also be careful when
you exercise, especially in hot weather.
Serious side effects include severely impaired vision, confusion,
clumsiness, seizures, trouble breathing, fast heartbeat, chest pain,
and slurred speech. Contact your doctor immediately or seek emergency
medical care.
Possible Drug Interactions
- amantadine (Symmetrel)              
        - atenolol (Ternormin)
- antacids (Maalox, Mylanta, TUMS)     - digoxin (Lanoxin)
- anti-diarrhea (Kaopectate, Pepto-Bismol, Amphogel)
- phenothiazines (Thorazine, Compazine, Prolixin, Mellaril)
- tricyclic anti-depressants (Elavil, Aventyl, Pamelor, Tofranil,
Sinequan)
Leuprolide Acetate (Lupron®)
This medicine is given by injection to treat advanced prostate cancer.
It produces an effect of castration as it shuts down testosterone
production from the testicles. As other hormonal treatment of prostate
cancer, it helps lessen the symptoms of this disease, but it is
not a cure. Women may be prescribed this medicine for several gynecological
conditions.
How is it given?
The injection (shots) is given deep into a muscle (usually the buttock
or thigh). Several formulations are available including one-month
and multi-month (usually 3 months) dosing, with the drug slowly
released over these time periods.
When starting this medicine, there is usually a testosterone surge,
which can worsen any voiding symptoms or bony pain. This effect
is blunted by using another medicine (an anti-androgen) for the
first few weeks of treatment.
Please Note
Common side effects include hot flashes, night sweating, fatigue
or loss of stamina, sexual problems, decreased or loss of erections,
and loss of appetite.
Long-term use of this medicine is associated with anemia (low red
blood cell count), osteoporosis, and elevation of total blood cholesterol
and triglycerides.
If you are experiencing severe problem with urination or bladder
emptying, intractable bony pain, loss of strength in your arms or
legs, immediately contact your doctor or seek emergency care.
No significant drug interactions have been reported. Be sure that
you tell your doctors about all medicines you are taking, including
over the counter drugs and natural remedies.This medicine is a fluoroquinolone
antibiotic used to treat urinary tract infections. It may also be
used by other physicians to treat other bacterial infections in
other parts of the body.
Proper Use
This medicine may be taken by mouth (a pill) or given by injection
(intravenous). When given orally, it can be taken with or without
food. Avoid taking this medicine around the time (usually 2 hours)
of other drugs, especially iron medicine, antacids containing aluminum
or magnesium, multivitamins, sucrafate (Carafate), and didanosine
(Videx).
A typical dose is once a day.
Please Note
Do not take with antacids.
If you are a diabetic using insulin or taking diabetes medicines
by mouth and you have symptoms of low blood sugar, contact your
doctor right away. Symptoms of low blood sugar include confusion,
shaking, weakness, strong hunger, cold sweats, headache, nausea,
vision problems, and feeling faint.
Tell your doctor if you have a seizure condition. If you have a
seizure while taking this medicine, stop taking it and contact your
doctor or seek emergency medical attention.
Allergic reactions can present in varying degree. Serious reactions
include hives, severe itching, tightness in your chest, and trouble
breathing. Contact your doctor right away or seek emergency medical
care.
This medicine may make you dizzy or drowsy. Do not drive or operate
machinery unless you are fully alert. Your skin may have increase
sensitivity to the sun while taking this medicine. Use sunscreen
and avoid long exposure to the sun. You may also feel increase effects
of caffeine in coffee, black tea, and colas.
Women should not take this medicine during pregnancy or when breast
feeding.
Possible Drug Interactions
- antacids containing aluminum or magnesium
- didanosine (Videx)
- insulin and other oral diabetes drugs
- multivitamins or supplements containing iron or zinc
- nonsteroidal anti-inflammatory drugs (NSAIDS): ibuprofen, Motrin,
Advil, Naproxyn, Orudis, Relafen, Indocin
- sucrafate (Carafate)
- theophylline (Theo-Dur, Slo-Bid)
- warfarin (Coumadin) or other blood thinners
Nitrofurantoin (Macrobid®, Macrodantin®, Furadantin®)
This is antibiotic used to treat bacterial infections of the urinary
tract.
Proper Use
Take this medicine with food or milk to lessen stomach upset and
to increase absorption. Depending on the specific clinical situation,
dosing may vary from once daily up to multiple times per day. Always
take the medicine as prescribed by your doctor.
Please Note
Common side effects include diarrhea, stomach upset, nausea, and
vomiting. Serious side effects are fever, chest pain, trouble breathing,
hives, generalized rash, yellowing of eyes or skin, and numbness
or pain in your hands or feet. Contact your doctor right away or
seek emergency medical attention.
This medicine may darken the color of your urine from yellow-brown
to brown. It may also cause a false urine sugar test. Check with
your doctor before making any changes in your diet or medication.
Women: Breast-feeding is not recommended while you are taking this
medicine.
Possible Drug Interactions
- antacids containing magnesium
- probenecid (Benemid)
- sulfinpyrazone (Anturane)
Saw Palmetto (Natural Remedy)
What is it?
It is a member of the fan palm family. It grows to about 10 feet
tall, with leaf clusters that can reach a length of 2 feet or more.
The plant grows in many areas across southern United States, and
is actually the "state plant" of South Carolina. Saw palmetto produces
a brownish-black berry. The ripe fruit of the plant is in medicines.
The scientific names are Serenoa repens, Serenoa serrulata, and
Serenoa serrulatum. The common names include saw palmetto, sabal,
American dwarf palm tree, and cabbage palm.
How is saw palmetto used in urology?
Be aware that medical indications of natural remedies are not approved
by the Food and Drug Administration (FDA). They are classified as
dietary supplements, and are not subject to the same scrutiny and
regulations as prescription medicines.
Saw palmetto has been reported to be used for the relief of voiding
symptoms secondary to prostate gland enlargement, irritable bladder
(causing pelvic pain and frequent urination), and to increase sperm
production.
How is saw palmetto taken?
It is taken by mouth as a tea, capsule, tablet, or liquid.
What are the side effects?
No serious side effects have been reported. However, there have
been reports of headaches and diarrhea if taken in large amounts.
What special precautions are there?
- If you are pregnant, trying to become pregnant, or breast-feeding
you should not take saw palmetto.
- Some natural remedies may have the same effects as prescription
drugs. If you have any unusual effects while taking any natural
remedy, stop and get advice from your doctor.
- "natural" does not always mean safe. Report any unusual reactions.
- Lack of standardization may result in products with different
strengths and effects.
- Lack of quality control may allow contamination of products.
- Infants, children, and the elderly should not use natural remedies
without advice from a doctor.
- Follow dosage recommendations on the package. Do not increase
dosages.
Sildenafil Citrate (Viagra®)
This medicine is taken by men for the treatment of impotence (erectile
dysfunction).
Proper Use
Take the dosage exactly as prescribed for you by your doctor. Do
not increase dosage without your doctor's advice. Do not take this
medicine more than once a day.
The recommended dosage is one 50-mg tablet. However, you may need
to take as little as 25 mg or as much as 100mg. An adequate trial
is needed before consideration of dosage increase.
This medicine is best taken on an empty stomach, usually about 1
hour before expectation of sexual activity.
Please Note
Elderly men who have not had sexual intercourse for a long time
should be cautious when they begin to have sex again, especially
if they have heart problems. In these particular cases, an evaluation
with your primary care doctor or your heart doctor is advised.
This medicine is approved for men only.
Do not take this drug (1) if you are taking any nitrate products
(nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate)
for the treatment of angina or chest pain or to control your high
blood pressure, and (2) if you have any heart disease.
Sexual activity is considered strenuous activity, particularly in
elderly men with heart problems who are at risk of heart attacks
that may be fatal. You should discuss your situation with your primary
care physician or heart physician before taking this medicine.
Common side effects include headache, facial flushing, stomach upset,
stuffy nose, and abnormal vision (light sensitivity or blurred vision).
Possible Drug Interactions
- cimetidine (Tagamet)           - erythromycin
(Erythrocin, EES)
- itraconazole (Sporanox)       - ketoconazole (Nizoral)
- mibefradil (Posicor)             - nitrates
(nitroglycerin, Imdur, Isordil)
- protease inhibitors (Novir, Fortovase, Invirase, Crixivan, Viracept,
Agenerase)
- rifampin (Rifadin, Rimactane)
Be sure to inform all your physicians about all medicines you are
taking, including over the counter products, vitamins, and natural
remedies.
Soybean (Natural Remedy)
The soybean plant grows 1 to 5 feet tall, with bean pods containing
up to 4 oval seeds, which are yellow to brownish in color. This
plant was cultivated in China as far back as the 11th century BC.
Current U.S. production is about 49% of the world's supply. The
scientific name is Glycine max. Common names are soy, soybean, and
soya.
How has soybean been used?
Remember that natural remedies are classified as dietary supplements
by the FDA, and are not subjected to the same scrutiny and regulations
as prescription drugs.
Food use: Soy is an important food
source that is nutritious and low cost. Examples are soybean milk,
soybean flour, soybean curd, tofu, fermented soybean paste, soybean
sprouts, soy sauce, soybean oil, soy protein drinks, and livestock
feeds. Soy is used to make some infant formulas, especially for
babies who are allergic to milk.
Hormonal effects: Soybeans contain
a substance that is similar to the female hormone, estrogen. As
such, it has been used to help with symptoms of menopause (hot flashes),
and possibly may be used to help reduce osteoporosis.
Anticancer effects???: In certain
parts of the world in which there is a high intake of soy products,
there is a lower prevalence of breast cancer, endometrial cancer
and prostate cancer.
Cardiovascular disease: Asian countries
with higher soy intake appear to have lower rates of heart disease.
Gastrointestinal effect: Soybean fiber
can prevent constipation, and possibly reducing the incidence of
bowel diseases.
Possible Side Effects
Most people have no problems with soy. Infants with a cow's milk
allergy may have a reaction to soy milk products as well. There
is also some concern about the phytoestrogens in soy-based infant
formulas. Discuss your concern with your pediatrician.
Large amounts of soybean oil may increase bilirubin in your blood.
See your doctor if your skin or eyes look yellow (jaundice).
Sulfamethoxazole-Trimethoprim (Bactrim®, Septra®,
Sulfatrim®, SMZ/TMP)
This is an antibiotic used to treat bacterial urinary tract infections.
Proper Use
This medicine comes in liquid and pill forms, and works best when
taken with a full glass of water 1hour before or 2 hours after meals.
There is also an intravenous preparation.
Dosing may vary for different clinical indications. Take as directed
by your physician.
Please Note
Allergy to sulfa drugs is common. Serious allergic reaction includes
hives, rash, bloody urine, yellowing of your eyes and skin, tightness
in your chest, and trouble breathing. Contact your doctor right
away or seek emergency medical care.
This medicine may make your skin more sensitive to the sun. While
you are taking this medicine, avoid long exposure to the sun. While
you are in the sun, wear protective clothing and sunscreen lotion.
Do not use a sunlamp.
Women who are pregnant or breast-feeding, please inform your doctor.
Other milder side effects include headache, dizziness, nausea, vomiting,
and diarrhea.
Possible Drug Interactions
Talk to your doctor is you are taking any of these medicines:
- cyclosporine (Sanimmune, Neoral)
- indomethacin (Indocin)
- methotrexate
- phenytoin (Dilantin)
- probenecid (Benemid)
- salicylates (aspirin)
- thiazide diuretics
- tolbutamide (Orinase)
- warfarin (Coumadin)
Birth control pills may be less effective while you are taking this
medicine. Talk to your doctor if you need birth control.
Tamsulosin Hydrochloride (Flomax®)
This medicine is the first medicine developed to relieve the symptoms
of an enlarged prostate. It does this be relaxing the smooth muscle
in the prostate and around the bladder neck.
Proper Use
Take your dose one-half hour after the same meal each day. If you
miss a dose, take it as soon as you remember unless it is almost
time for the next scheduled dose. In that case, skip the missed
dose and take the next one as directed. Do not take double doses.
Do not chew, crush, or open the capsules. Swallow them whole.
Please Note
This medicine may make you dizzy or feel like you may faint. Do
not drive or operate machinery unless you are fully alert and clearheaded.
This medicine is not intended for any use in women or children.
Some abnormal ejaculation (less volume) may occur. Ask your doctor
about this.
Other side effects include headache, weakness, drowsiness, runny
nose, diarrhea, and nausea.
Contact your doctor for worsening dizziness or fainting.
Possible Drug Interactions
- blood pressure medicines (prazosin, doxazosin, terzosin). Do not
take concurrently.
- cimetidine (Tagamet)
- warfarin (Coumadin)
Tolterodine Tartrate (Detrol LA®)
This medicine is being used to treat a variety of lower urinary
tract disorders, most commonly for women (some men) with overactive
urinary bladders.
Proper Use
Take this medicine exactly as directed by your doctor. Do not take
more or less, or take it longer than prescribed. With the new long-acting
formula, dosing is now once a day. If you miss a dose, take it as
soon as you remember unless it is almost time for the next scheduled
dose. In that case, skip the missed dose and take the next one as
directed. Do not take double doses.
Please Note
Do not take this medicine if you are not able to urinate.
If you have closed-angle glaucoma, inform your doctor of this condition.
This medicine may cause blurred vision. Do not drive or operate
machinery unless your vision is perfectly clear.
Women: Tell your doctor if you are pregnant or breast-feeding. Do
not breast-feed while you are taking this medicine.
Side effects include dry mouth, blurred vision, upset stomach, headache,
constipation, dizziness, confusion, fatigue, and nausea. If you
cannot urinate, contact your doctor immediately.
Possible Drug Interactions
- clarithromycin (Biaxin)         - erythromycin
(Erythrocin, EES, Eryped)
- itraconazole (Sporanox)       - ketoconazole (Nizoral)
- miconazole (Monistat)
Be sure to inform all your doctors about all medicines you are taking,
including over the counter products, vitamins, and natural remedies.
*  This
advisory includes selected information only and may not
include all the side effects of this medicine or interactions
with other medicines. Ask your doctor or pharmacist for more
information or if you have any questions.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
This content is reviewed periodically and is subject to change
as new health information becomes available. The information
is intended to inform and educate, and is not a replacement
for medical evaluation, advice, diagnosis or treatment by a
licensed physician.
*  This
information is not intended to substitute for a consultation with
a urologist. It is offered to educate patients on the basis of
urological conditions in order to get the most out of their office
visits and consultations. Please see our web page disclaimer
for addition information.
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